Non-Invasive Ventilation and Surfactant Therapy

The lungs of premature infants are more vulnerable than term infants to the effects of invasive positive pressure ventilation. Published literature supporting the use of non-invasive respiratory support with CPAP, bi-level CPAP mode, such as, SiPAP and Nasal Intermittent Positive Pressure Ventilation (NIPPV), and surfactant administration strategies are discussed. This review focuses on non-invasive respiratory support strategies and selective early use of surfactant that may reduce the incidence of bronchopulmonary dysplasia. *Corresponding author: Rangasamy Ramanathan, USC Division of Neonatal Medicine, LAC+USC Medical Center and Children’s Hospital Los Angeles, 1240, North State Street, IRD-820, Los Angeles, CA 90033, USA, E-mail: [email protected] Received July 18, 2012; Accepted September 11, 2013; Published September 13, 2013 Citation: Ramanathan R, Paz P, Biniwale M (2013) Non-Invasive Ventilation and Surfactant Therapy. J Pulmon Resp Med S13: 006. doi:10.4172/2161-105X.S13006 Copyright: © 2013 Ramanathan R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.